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No studies were excluded on issues of methodological quality. These populations represent the target groups for health education programmes, for opportunistic intervention and for decisions to investigate for possible malignancy. GPs have been criticised for both too few and too many urgent referrals of patients with symptoms of possible cancer. Read more on NSW Health website. Guidance to aid a GP in determining whom to investigate or refer exists but recommendations vary. Clinical presentation and management of stage 1 cervical adenocarcinoma: Duties of a doctor. An epidemiological survey of symptoms of menstrual loss in the community.